Antiphospholipid antibodies in stroke

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Antiphospholipid antibodies and stroke.

The clinical study of stroke is a recent occurrence. The clarion call awakening interest consisted of two reports that appeared during the years following World War II : the detailed description by Kubik and Adams [1) of the clinical and pathologic findings in patients with basilar artery occlusion, and C. Miller Fisher's monograph [2] directing attention to the signs and symptoms found in pati...

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Antiphospholipid antibodies and stroke in young women.

BACKGROUND AND PURPOSE Antiphospholipid antibodies have been associated with ischemic stroke in some but not all studies. METHODS We performed a population-based case-control study examining antiphospholipid antibodies (anticardiolipin antibodies and lupus anticoagulants) using stored frozen sera and plasma in 160 cases and 340 controls enrolled in the Stroke Prevention in Young Women study. ...

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Antiphospholipid antibodies, prethrombotic states, and stroke.

Prethrombotic states are pathologic conditions in which blood coagulation, platelet function, or fibrinolysis have been altered to favor thrombosis. Epidemiologic studies suggest that prethrombotic states may occur in some patients with stroke who have atherosclerotic risk factors, but the details of these relationships remain poorly understood. Recently, many of the natural inhibitors of throm...

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Clinical and laboratory findings in patients with antiphospholipid antibodies and cerebral ischemia. The Antiphospholipid Antibodies in Stroke Study Group.

We reviewed the clinical and laboratory data of 128 patients with cerebrovascular disease and antiphospholipid antibodies. Cases were evenly divided between men and women, and the mean age of the study group was 46 years. Cerebral infarction occurred in 97 patients, and transient hemispheric ischemic attacks without stroke were recorded in 19; 12 suffered ocular ischemia. Systemic lupus erythem...

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Prevalence of Antiphospholipid Antibodies in Syrian Patients with Thrombosis

Background: Antiphospholipid antibodies (aPL) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. Objective: To study the prevalence of aPL in patients with thrombosis at Aleppo University Hospitals, Syria. Methods: One hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. Anticardiolipin antibodies (...

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ژورنال

عنوان ژورنال: Journal of Postgraduate Medicine

سال: 2010

ISSN: 0022-3859

DOI: 10.4103/0022-3859.62417